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Publish Date : 9/2/2004 1:16:00 PM Source : SkinCareIndia Health News The accumulation of beta-amyloid in Alzheimer's disease (AD) is only one of the results of proteolytic cleavage of amyloid precursor protein (APP).
Cleavage by beta- and gamma-secretase leads to A-beta production, whereas alpha-secretase cleavage results in a soluble form, sAPP-alpha. This week, Stein et al. examine the apparent neuroprotective role of sAPP-alpha in mice. Using antibody interference and siRNA knockdown techniques, the authors demonstrate, in hippocampal slices and in vivo, that sAPP-alpha provides the mutant mice with the protective armor of increased TTR and IGF-2 expression, thus preventing tau phophorylation and neuronal death. Too bad that sAPP-alpha is not at high levels in Alzheimer's patients. Thor D. Stein, Nicholas J. Anders, Charles DeCarli, Sic L. Chan, Mark P. Mattson, and Jeffrey A. Johnson. |
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Cervical cancer vaccine breakthrough
Publish Date : 11/15/2004 1:16:00 PM Scientists say they have tested a vaccine, Cervarix, that protects women from two strains of HPV (human papillomavirus) which are responsible for 70% of cervical cancers. Beyond Tactical Struggles over Public Policy -The President's Council on Bioethics Publish Date : 11/15/2004 1:15:00 PM An on-stage discussion with William F May, PhD. Bioethicist and Author Human mad cow disease, there are many different forms of it Publish Date : 11/15/2004 1:15:00 PM Depending on your genetic makeup, vCJD (Varian Mad Cow Disease) will manifest itself differently, say researchers. This means vCJD may be present in some areas without being detected (vCJD means the human form of mad cow disease). New online tool kit on HIV/AIDS prevention for sex workers Publish Date : 11/15/2004 1:11:00 PM GTZ, WHO and sex work networks share information and lessons learned - The German technical cooperation (GTZ) and the World Health Organization (WHO), in collaboration with sex work networks around the world..... Anti-drug driving campaign wins award Publish Date : 11/10/2004 7:34:00 PM A road safety initiative to stop people driving under the influence of drugs has won an award at the THINK road safety conference. Text Messaging Helps Patients in Developing Countries Manage HIV/AIDS Treatment Publish Date : 11/10/2004 7:33:00 PM Wired News on Thursday examined how HIV/AIDS treatment counselors in countries where health care .... Roche Diagnostics Launches Highly-sensitive Polymerase Chain Reaction System Publish Date : 11/10/2004 7:32:00 PM Roche Diagnositcs has begun sales of it's real-time polymerase chain reaction (PCR) system LightCycler ST300, a highly-sensitive gene analysis system. 3 by 5 Initiative for HIV 'Probably Will Not' Meet Treatment Publish Date : 11/10/2004 7:31:00 PM The World Health Organization's 3 by 5 Initiative goal of treating three million HIV-positive people with antiretroviral ........ Manufacturing Approval for Statmark Influenza Virus Detection Reagent Publish Date : 11/10/2004 7:30:00 PM Nichirei (TSe: 2871), a leading Japanese food processing company, has announced that it has ..... US Health Improvements Slowing - Alarm at High Infant Mortality Rates and Obesity Publish Date : 11/10/2004 7:28:00 PM Although the overall health of US residents continues to improve, health indicators show that ... Total Results : 3044 More News (Opens in New Window) : [1] 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 Next Page |
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