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How 'dirt' could educate the immune system and help treat asthma
Source : Asthma
Publish Date : 9/6/2005 2:48:00 AM

Scientists believe that knowing exactly which type of dirt provides the best 'education' for the immune system, could be key to providing new treatments for diseases such as asthma.

Speaking at the launch of the BA Festival of Science today, Professor Peter Openshaw, explains that a lack of exposure to dirt and common viral infections among children could be behind the rise in the levels of asthma.



Professor Openshaw, from Imperial College London, and based at St Mary's Hospital, says: "Although we have seen a dramatic decline in many previously common childhood infections over the past 100 years, we have also seen a considerable rise in the prevalence of diseases such as asthma. The increase in asthma cannot be blamed purely on changes in genetic risk, so must be down to environmental factors."

Scientists have called this the 'hygiene' hypothesis, with a lack of exposure to viruses and other environmental factors meaning children are not able to build up resistance, and can become more susceptible to disease later in life. They also believe having many older siblings, attending day care at an early age, or growing up on a farm can help in promoting resistance to disease.

Studies have shown that most common colds can help protect against wheezing in later childhood, and other childhood infections such as chickenpox also provide a level of protection.

Professor Openshaw adds: "The challenge now is to find ways of reproducing the protective effects of early childhood infections, while reducing the burden of actually getting these infectious diseases. Knowing exactly which 'dirt' provides the best education for the immune system, and how to mimic its affects in a cleaner environment, could be the key to reducing the rise in the prevalence of asthma and related diseases."



Atopical dermatitis and allergic rhinitis most common atopical illnesses in childhood after asthma
Publish Date : 10/9/2005 6:28:00 AM  
This was the conclusion of Ana Marķa Irujo Andueza in her PhD thesis defended recently at the Public University of Navarra.

Treating Severe Asthma in Children Based on Exhaled Nitric Oxide Levels
Publish Date : 10/4/2005 7:18:00 AM  
Physicians can better determine the most effective inhaled corticosteroid dose for children with moderate to severe allergic asthma ......

New research focus on asthma and airways, Australia
Publish Date : 10/4/2005 7:01:00 AM  
The Commonwealth Government has opened a new Cooperative Research Centre (CRC) for Asthma and Airways based at Sydney University.

Distress suffered by millions of asthma sufferers in Europe
Publish Date : 9/26/2005 3:36:00 AM  
A European patient body has called on governments across the continent to make asthma a priority, in a comprehensive report ......

Can a worm a day keep asthma at bay?
Publish Date : 9/6/2005 3:02:00 AM  
The key to preventing asthma and reducing allergies may lie in an unexpected source: parasitic worms.

How 'dirt' could educate the immune system and help treat asthma
Publish Date : 9/6/2005 2:48:00 AM  
Scientists believe that knowing exactly which type of dirt provides the best 'education' for the immune system.......

People with Crohn's and Colitis at Greater Risk of Asthma, Researchers Say
Publish Date : 9/3/2005 3:11:00 AM  
Canadian researchers looked at the relationship between IBD and common respiratory and neurological diseases.

Father With Asthma Is Key To Child's Airway Constriction
Publish Date : 9/2/2005 4:05:00 AM  
Children with asthma whose fathers have a history of the disease are at significantly greater risk for serious airway constriction .....

Brain structures contribute to asthma
Publish Date : 8/30/2005 2:19:00 AM  
The mere mention of a stressful word like "wheeze" can activate two brain regions in asthmatics during an attack, and this brain ......

Body's defense mechanism worsens asthma symptoms, study
Publish Date : 8/13/2005 2:37:00 AM  
MUHC scientists have discovered that our body's own defense mechanism causes some of the most serious asthma symptoms.

Total Results : 61  
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